Coronary Angioplasty

What is a Coronary Angioplasty?

Video: Live coronary angioplasty by Dr Binoy John

What are coronary arteries?

The function of the heart is to pump blood and thus supply energy to different parts of the body. For the heart to function as an effective pump it also needs blood, which is supplied to it via three arteries which run on its surface, called the coronary arteries. There are three coronary arteries. The one which supplies blood to the right side and inferior portion of the heart is called the right coronary artery. The left side of the heart is supplied by a short left main (LM) coronary artery which divides commonly into the left anterior descending (LAD) artery and the left circumflex (LCx) artery. Uncommonly there can be a third artery from the LM called the ramus intermedius artery. The coronary arteries have an average diameter of 2 to 4 mm. (For more information see: Coronary angiogram)

What is a block?

A block or stenosis is essentially made of fat or lipids and usually develops inside the coronary artery, over time, by a process called atherosclerosis. Some blocks may accumulate calcium deposits on it eventually, which can make the blocks hard as stone. (See Image)

A 99% block in the right coronary artery
A 99% block in the right coronary artery

Do all blocks produce a heart-attack?

When a significant block or stenosis develops inside a coronary artery, the blood supply or flow gets compromised and the heart is not able to get enough blood or oxygen it needs to pump. This can classically result in chest pain (angina) on exertion or at rest depending on the severity of the block. When a sudden complete blockage occurs to blood supply to the heart muscle by the formation of a sudden blood-clot inside the coronary artery, a heart-attack or acute myocardial infarction occurs.

Do all blocks need angioplasty or by-pass surgery?

Before a decision for an angioplasty or by-pass surgery is made, a coronary angiogram is first performed which will show the presence of number of blocks, the percentage of the blocks, the location of the blocks and the number of arteries blocked. Any significant block compromising blood flow to a large portion of the heart-muscle has to be treated. Depending on the location of the block and other comorbidities, the treatment options can be a by-pass surgery or angioplasty. Blocks less than 70% need just medical management. But some blocks which are more than 70% can also be managed with medicines depending on the location and area of supply.
 
What is a coronary angioplasty?

Coronary angioplasty is a non-surgical procedure by which one or many blocks in the coronary artery are opened with a balloon and then one or more stents (cylindrical tubular meshes commonly made of alloys) are placed or deployed across the block to re-establish the blood flow. (See images: 1. 99% block before stent and 2. After stent)

(Watch above video for steps and live narration)
RCA with 99% block
RCA with 99% block
RCA after stent
RCA after stent

 

Anaesthesia and pin-hole puncture:
Coronary angioplasty is performed under local anaesthesia in an awake patient, through a pin-hole puncture (usually 1.6 -3 mm in diameter) made on the artery of the leg (femoral artery), or hand (radial or ulnar artery), depending on whether the angioplasty is going to be done via the groin/leg or wrist/hand. The local anesthesia is first given over the skin and after the anesthesia sets in, a small needle is used to puncture into the artery and then a wire is passed through the needle into the artery. Thereafter a sheath or tube is placed through the skin into the artery through which the entire angioplasty would be performed.

 

Procedure and steps of an angioplasty:
In a coronary angioplasty, a catheter or tube, which is larger than the one used for an angiogram called the guiding catheter is first advanced through the sheath already placed in the artery, over a wire, onto the mouth of the coronary artery in which the angioplasty has to be performed. (See image)
 

Once the artery is engaged, a wire is passed through the catheter to cross the block. Thereafter, a balloon is taken over the wire and placed across the block. The balloon is then inflated from outside with an in-deflator to open the block. (See image)

Wire and balloon are positioned in the RCA and the block is opened by inflating the balloon
Wire and balloon are positioned in the RCA and the block is opened by inflating the balloon

The balloon is then removed. After balloon dilatation, a stent, which is a tubular mesh, often coated with a medication has to be deployed across the block to prevent a re-block. The stent which comes pre-mounted on a balloon is advanced over the wire and positioned across the block. (See image)

Stent is positioned across the block and deployed
Stent is positioned across the block and deployed

When the balloon of the stent is inflated the stent gets apposed across the block on to the inside of the artery. The outward radial strength property of the stent keeps the stent open and keeps it well apposed to the arterial wall.  (See image)

An excellent result and blood flow are achieved after stent deployment
An excellent result and blood flow are achieved after stent deployment

After the stent is deployed, the balloon is removed. Thereafter a larger balloon is often used to make the stent larger and get the stent better apposed to the arterial wall. Once a good result is confirmed the balloon, the wire and guiding catheter are removed from the artery. The sheath on the hand or leg is removed last. Usually the patient is discharged after 24 to 48 hours, depending on the complexity of the procedure and the course in the hospital, after an over-night observation in the coronary care unit. It is always safer for the patient to be in-hospital for at least 36 hours after the procedure.

What are the types of angioplasties? 

Coronary angioplasty can be in a single artery when it is called Single vessel angioplasty or it can be in multiple arteries when it is called Multi-vessel angioplasty. When it is performed on calcified blocks it is a more complex procedure called Rotablation angioplasty and when it is performed in a patient with an ongoing heart attack it is called a Primary angioplasty. There are various other complex angioplasties which are detailed in the respective sections.